I use exped bags and tried to look for the litreage of them, depending how big your rucksack is, depends what size you feel you'd want. I use a Deuter Guide 35+ litre sack..so went for an XL, in the winter its full and my gear is protected, in the summer I just roll it down and job done.
I agree with Mike, lots of different drysacks mite be nice and organised, but they do add weight. I personally just use two, the XL for my kit, and then a Small which is kept at the top at all times which has head torch, first aid kit, survival bivy, hat n gloves...the important stuff close at hand.
Jacko.